New rapid typing method developed to control monkeypox by Molecular Biology Systems (MBS) in collaboration with UMC Amsterdam and Danish Rigshospitalet
GOES, Netherlands, August 2, 2022 /PRNewswire/ — As part of the global effort to combat monkeypox, a new rapid typing method to trace monkeypox virus strains has been developed by the Dutch company Molecular Biology Systems (MBS) in collaboration with the Department of Medical Microbiology and Prevention of Infectious Diseases of Amsterdam UMC and researchers from the Danish Rigshospitalet. In addition to being fast, this new method allows the simultaneous analysis of several samples. In this way, the genetic characterization of the monkeypox virus can be used in source and contact analyzes and help determine measures of choice. Analyzing multiple samples simultaneously reduces the cost per sample, which means more information for the same cost. A photo can be found https://www.nextgenpcr.com/product/mbs-nextgenpcr-ultrafast-thermocycler/:
The method was first tested in amsterdam Region; this has led to new knowledge regarding the genetic diversity of the monkeypox virus. This method was used to investigate the infection of the first child of the Netherlands. The characterization of mutations in the child virus was compared to other monkeypox viruses in the region. In a publication by July 21, 2022, in the widely read scientific journal Euro Surveillance, the research into this case and the infectious chain is described. Using source and contact analyses, no links to other cases were found. There may be more undetected infections than expected so far.
(Euro Surveillance publication: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2022.27.29.2200552)
An important advantage of this newly developed typing method is also its ease of use for other viruses. By integrating this technique into source and contact surveillance at an early stage, earlier insight into the spread of new viruses can be gained. This will allow rapid, concrete and precise action.
The above is in line with the WHO strategy for monitoring viruses worldwide, particularly monkeypox. Second meeting of the International Health Regulations (2005) Emergency Committee (IHR) regarding the outbreak of monkeypox in several countries (who.int)
Several leading international laboratories have indicated their intention to use this method for genomic monitoring of monkeypox.
About Molecular Biology Systems
Molecular Biology Systems, BV, founded in 2015, is a molecular biology solutions company based in the Netherlands. Our NextGenPCR thermal cycler uses patented technology to reduce PCR amplification from hours to minutes. NextGenPCR, the PCR technology of the future, available now.